![]() The other eight trials involved low-dose vitamin E users. When the data for these trials was re-evaluated, through a process called a meta-analysis, nine of 11 trials involving high-dose vitamin E (400 IU per day, or more) showed an increased risk of death. Follow-up periods ranged from 1.4 years to 8.2 years. Risk of death was estimated by comparing the death rates in both groups. All of the studies involved use of a control group taking a dummy pill, or placebo. The 19 studies took place between 19 and involved more than 136,000 patients in North America, Europe and China. Nine of these studies tested vitamin E alone 10 tested its use in combination with other vitamins. In the current study, the Johns Hopkins team re-analyzed raw data from 19 major clinical trials, sorting information by whether high- or low-dose levels of vitamin E were taken. The study results indicated that these high-dose supplements were associated with a higher risk of death. Vitamin E capsules, used as supplements, typically contain 400 IU to 800 IU. But our study shows that use of high-dose vitamin E supplements certainly did not prolong life, but was associated with a higher risk of death." "A lot of people take vitamins because they believe it will benefit their health in the long term and prolong life. Miller III, M.D., Ph.D., associate professor of medicine at The Johns Hopkins University School of Medicine. If people are taking a multivitamin, they should make sure it contains no more than a low dose of vitamin E," said study lead author and internist Edgar R. "Our study results do not support the use of high-dose vitamin E supplements. The study results showed that people taking vitamin E supplements of 400 IU or more per day had an increased risk of death. The Johns Hopkins team is scheduled to present its findings at the American Heart Association's Scientific Sessions 2004 in New Orleans, La., with simultaneous publication of their study in the Annals of Internal Medicine online Nov. These results should be of concern to the millions of Americans who take vitamin E supplements for perceived health benefits. Researchers at Johns Hopkins report that use of high-dose vitamin E supplements, in excess of 400 IU (international units), is associated with a higher overall risk of dying. STUDY SHOWS HIGH-DOSE VITAMIN E SUPPLEMENTS MAY INCREASE RISK OF DYING
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |